Protein Restriction & Longevity Pathways

Can protein restriction slow aging?

Yes. Reducing protein intake influences pathways like IGF-1 and mTOR that regulate growth and aging.

Explanation

High protein intake, especially from animal sources, raises IGF-1 levels, which drive growth and accelerate cellular aging. Moderate protein restriction reduces IGF-1 and mTOR activity, both of which are associated with longer lifespan in multiple models.

However, protein restriction must be balanced with the need to preserve muscle mass and function, particularly in older adults. Plant proteins may offer a healthier balance, providing adequate nutrition with lower IGF-1 stimulation.

Practical Emphasis: Aim for moderation — adequate but not excessive protein, with an emphasis on plant sources. Adjust based on age, activity, and health goals.

Takeaway (Action Tip)

Use protein moderation to balance muscle preservation with longevity pathways.

Reference

Cell Metabolism, 2014 – Protein Intake and IGF-1 Pathways in Aging

How Memorial Longevity Clinic Can Help

We measure IGF-1 levels, muscle mass, and dietary protein balance to help patients align protein intake with both longevity and functional health.

Disclaimer

The information provided on this page is for educational and informational purposes only and is not intended as medical advice. This content should not replace professional medical consultation, diagnosis, or treatment. Always seek the guidance of your physician or other qualified healthcare provider before making any changes to your health, lifestyle, or treatment plan.

Schedule a service or consultation at the link below to get started with your longevity journey.